If your sound keeps cutting out seemingly randomly for your wirelessly headset with this motherboard then try plugging it into the other USB slots (not the blue ones, the red ones). It seems to have fixed my issue. Seems the other ones may not have enough power to support the power draw.
Found the fix here: Audio issues MSI Pro B650-S Wifi | MSI Global English Forum
Have you use another headphone to check for the symptom?
I think I found the solution to my issue :
The USB 3.2 Gen 1 ports connect to something called “Hub-1074” and I guess those aren’t good enough for USB headsets. I at first thought that it was an issue with the board because the chipset driver updates reduced the problem, but didn’t fix it. I then tried connecting with a different headset that uses 3.5mm jacks and it worked without issues, so now I have connected my USB headset to one of the USB 3.2 Gen 2 ports that connect to the CPU, and so far I haven’t had any audio issues.